A comparison of subject, informant, and clinician report in cognitively normal elderly and mild cognitive. Scales designed to more thoroughly assess apathy with multiple items include the 14item apathy scale, the apathy inventory, and the apathy evaluation scale aes. Informants can probably report apathy symptoms most accurately because. Aes c, apathy evaluation scale clinician assessment. Apathy evaluation scale aes30 is based upon marins conceptualization of apathy. To compare the three aes sub scales subjectreported aess, informant reported aesi, and clinicianreported aesc over time in individuals at risk for ad due to mci and advanced age cognitively normal. Ebif c, emotion behavior index form clinician assessment. Following convention established by the scale s developer, we designated each. Assessment of the psychometric properties of the apathy evaluation scale. The lille apathy rating scale lars comprises 33 queries belonging to nine domains, each corresponding to a clinical manifestation of apathy. To compare the three aes subscales subjectreported aess, informant reported aesi, and clinicianreported aesc over time in individuals at risk for ad due to mci and advanced age cognitively normal. Apathy is a diminished goaldirected behavior stemming from a lack of motivation. Yes population adult domain behavioural function type of measure informant or selfreport scale icfcodes b1 description the frsbe is designed to measure changes in behavior as a consequence of frontal systems dysfunction. Rating scale for aggression in the elderly rage cohen mansfield agitation inventory cmai and pittsburgh agitation inventory pai rating anxiety in dementia raid apathy evaluation scale aes cornell scale for depression in dementia csdd and geriatric depression scale gds the latter for community settings 18.
Properties of the apathy scale as for use on parkinson s. The aes can be given to individuals, their significant others, and their clinicians to compare responses. Operationally, the aes treats apathy as a psychological dimension defined by simultaneous deficits in the overt behavioral. Apathy was quantified using the aes, consisting of 18 items relating to apathy, each scored on a 4point likerttype scale total aes score range 1872 with lower score indicating greater apathy. The apathy evaluation scale aes is the most widely used. Apathy is usually defined as reduced interest and participation in various activities. Scale for the assessment of negative symptoms sans and positive and negative symptom scale panss are not included since primarily used in patients with schizophrenia. In this regard, the widely used apathy evaluation scale aes has been identified as promising since it is one of the most robust measure for assessing apathy for several diseases. Development and validation studies are described in rs marin, rc biedrzycki, s firinciogullari. Two scales occur most frequently in the literature clarke et al. Developed by robert marin in 1991, the apathy evaluation scale aes is a way of measuring as related to brainrelated pathology. Apathy and depressed mood in acquired brain damage.
The apathy evaluation scale, informant version aesi. Jun 20, 2019 apathy scale starkstein pdf june 20, 2019 background. The primary outcome for apathy apathy evaluation scaleclinician and secondary outcomesforcognitionminimentalstateexamination,modi. The apathy evaluation scale was developed by robert s. The apathy evaluation scale department of psychology. To develop an apathy rating scale using a structured. However, in clinical research and in most pharmacological intervention studies, apathy is. Apathy is the most common behavioral change reported in amyotrophic lateral sclerosis als. To compare the three aes subscales subjectreported aess, informant reported aesi, and clinicianreported aesc over time in individuals at risk for ad due to mci and advanced age cognitively normal cn elderly. Apathy aes scale evaluation aged care tests, assessments and. First, we studied apathy in a sample of 32 ad patients. Reliability and validity of the apathy evaluation scale, psychiatry research, 38. Apathy following traumatic brain injury box 1 diagnostic criteria for apathy 1.
The lille apathy rating scale lars, a new instrument for. For each statement, circle the answer that best describes the subjects thoughts, feelings, and activity in the past 4 weeks. Apathy and anxiety are early markers of alzheimers disease. If yes, the informant then rates both the severity of the symptoms present within the last month on a 3point scale and the associated impact of the symptom manifestations on them i. Centered around evaluation, the scale can either be selfinformed or otherinformed. Reliability and validity of the apathy evaluation scale. Jul 24, 2015 the apathy evaluation scale aes is a promising tool for measurement of apathy in prodromal and possibly preclinical ad. In addition to acute motor, sensory, and language impairments, subacute and chronic neuropsychiatric disturbances after stroke can have major impact on activities of daily living. The apathy evaluation scale aes proposed by marin et al 4 is currently the scale most often used to assess apathy. Aes10 c indicates apathy evaluation scale modified to 10 items clinician assessment. The three versions of the test include self, informant such as a family member, and clinician. Imaging markers associated with the development of post.
To develop an apathy rating scale using a structured standardised interview capable of distinguishing between the conditions various features. The apathy evaluation scale aes is a promising tool for measurement of apathy in prodromal and possibly preclinical ad. Jan 01, 2007 assessment of the psychometric properties of the apathy evaluation scale. Methylphenidate for apathy in communitydwelling older.
The aes, which uses 18 specific items to quantify apathy within a scoring range of 18 to 72, is an especially promising metric for apathy in ad. He defined apathy as lack of motivation not attributable to diminished level of consciousness, cognitive impairment, or emotional distress. The prevalence, clinical correlates and treatment of. Apathy is a common neuropsychiatric symptom in alzheimers disease ad dementia and mild cognitive impairment mci. I want to ask you some questions about your quality of life and have you rate different aspects of your life using one of four words. Conceptually, apathy is defined as lack of motivation not attributable to diminished level of consciousness, cognitive impairment, or emotional distress. Apr 24, 2008 apathy was also assessed in a patient. Detecting apathy accurately may facilitate earlier diagnosis of ad. A comparison of subject, informant, and clinician report in cognitively normal elderly and mild cognitive impairment. With record low turnouts at the general election, politicians are lecturing us not to be so apathetic. For the clinician and informant versions of the scale, two factors were identified which accounted for 51. Reliability of the apathy evaluation scale in myotonic. Psychometric properties of apathy scales in dementia. To compare the aes subscalessubjectreported aess, informantreported aesi, and clinicianreported aescover time and investigate apathys relation to cortical atrophy in mci and cognitively normal cn elderly.
Scale for evaluating the psychological impact of neuropsychiatric symptoms reported to be present kaufer et al, jags, 1998. The interview is structured and the questions should to be posed exactly as stated. We further hypothesized that in mci the informant and clinician. Table 1 presents the results of the factor analysis for the three versions of the aes. Apathy and anhedonia rating scales in parkinsons disease. Objective this study was designed to establish the validity and reliability of the apathy inventory ia, a rating scale for global assessment of apathy and separate assessment of emotional blunting, lack of initiative, and lack of interest. Its reliability and validity for measuring apathy in different pathological conditions have been demonstrated. The purpose of this study was to investigate the cutoff score, reliability and validity of the japanese version of the aesi aesij. The lille apathy rating scale lars, a new instrument for detecting and quantifying apathy. The aes addresses characteristics of goal directed behavior that reflects apathy including behavioral, cognitive, and emotional indicators. Request pdf psychometric properties of a german version of the apathy evaluation scale apathy is a common feature of a variety of different psychiatric, neurological, and medical disorders. Development and validation studies are described in marin et al. The as 8 is based on the apathy evaluation scale aes by marin.
Apathy project gutenberg selfpublishing ebooks read. Associations of apathy with important variables in dementia care, such as cognitive. Convergent and discriminant validity of apathy evaluation scale clinician informant self apathy depression anxiety apathy depression anxiety apathy depression clinician apathy depression 0. Briefly, apathy was diagnosed whenever patients had 1 poor or no motivation as rated with item 7 on the apathy scale, 2 poor or no interests as rated with items 1 and 2 or effort as rated with items 4 and 9, and 3 feelings of indifference or lack of emotions most or all of the time as. The apathy evaluation scale aes was developed by marin 1991 as a method for measuring apathy resulting from brainrelated pathology. The one most widely used is the apathy scale, a questionnaire that people with pd fill out in the doctors office. The present study aimed to investigate whether the aes is an adequate measure of apathy as a multidimensional disorder. Validation of the italian version of the apathy evaluation. Psychometric properties of a german version of the apathy. Developed by robert marin in 1991, the apathy evaluation scale aes was the first method developed to measure apathy in clinical populations. The apathy evaluation scales scoring for individuals with.
However, different cutoff scores for the apathy evaluation scale informant version aesi, an international apathy scale, have been used in previous studies. Marin, 1991 see references for selfrated and informantrated versions of. Objective to compare the three aes subscalessubjectreported aess, informantreported aesi, and clinicianreported aescover time in individuals at risk for ad due to mci and advanced age cognitively normal. The aforementioned scales and sub scales test apathy as a singular concept whereas marin et al. Behavioral who number of response estimated setting and. Apathy severity was measured mean 3 months sd 3 from baseline with the swedish version of the self aess and informantrated aesi version of apathy evaluation scale aes, where higher scores indicate a higher level of apathy symptoms range 1872. There is a lack of motivation relative to the patients previous level of functioning or the standards of their age and culture as indicated either by subjective account or observation by others. Reliability and validity oas overt aggression scale. Three versions of the aes clinician, informant, and selfrated were evaluated for 123 subjects, ages 5385, meeting research criteria for right or left hemisphere. Marin, 1991 see references for selfrated and informant rated versions of aes, the response options are not at all true, slightly true, etc. Apathy evaluation scale self, informant, and clinician. Clinician aesc, informant aesi and selfrated aess versions. Although various scoring methods have been proposed, there is a lack of validated, standardised instruments for detecting apathy and assessing its severity.
Although the item starkstein apathy scale sas is recommended to screen for and measure the severity of apathetic symptoms in parkinson. The npiq is designed to be a selfadministered questionnaire completed by informants about patients for whom they care. To compare the aes sub scales subjectreported aess, informant reported aesi, and clinicianreported aescover time and investigate apathy s relation to cortical atrophy in. Sample version of the lille apathy rating scale lars. Statistical manual of mental disorders, fourth edition, text revision dsmivtr. Unified parkinsons disease rating scale not included as it is a single item for apathy that does not have any reliability measure. Apathy has been correlated with key neuroimaging biomarkers in ad patients including increased neurofibrillary tangle burden, reduced cerebral blood flow, reduced neuronal metabolism. Reliability and validity of the brief dimensional apathy scale. For each subject, three aes sub scale scores were collected, with each sub scale scored based on the impressions of a single reporter. If the response to the domain question is no, the informant goes to the next question. Cronbachs alpha and standardized alpha coefficients were 0.
Operationally, the aes treats apathy as a psychological dimension defined by. A comparison of subject, informant, and clinician report in cognitively normal elderly and mild cognitive impairment the harvard community has made this article openly available. This article presents evidence for the reliability and construct validity of the apathy evaluation scale aes. Aes i apathy evaluation scale informant aes s apathy evaluation scale self. The apathy evaluation scale aes is the most widely used measure of apathy. To compare the three aes sub scales subjectreported aess, informant reported aesi, and clinicianreported aesc over time in individuals at risk for ad due to mci and advanced age cognitively normal cn elderly. Reliability and validity of the apathy evaluation scale sciencedirect. The primary outcome for apathy apathy evaluation scale clinician and secondary outcomesforcognitionminimentalstateexamination,modi. The apathy evaluation scale aes has been used by clinicians to determine the presence of apathy in individuals with alzheimers disease, stroke, depression, and traumatic brain injury. Apathy is characterized by a marked loss of motivation, and presents itself across several neurodegenerative disorders, including alzheimers disease ad and related dementias. Lille apathy rating scale lars mapi research trust. Another is the lille apathy rating scale, which is administered as an interview between the person with pd and a medical professional.
The apathy evaluation scale, informant version aes i was developed by marin for evaluation of apathy in a patient based on interview of a person familiar with the patient. While the apathy evaluation scale aes has proved to be a psychometrically robust measure for assessing apathy, the german version aes d requires further validation. It is a frequent consequence of neurological and psychiatric disorders. The rating scale, which also can be administrated as an informant and self evaluation version, has shown good reliability and validity properties across various patient groups. Estimated time to administer setting and target population. Centered around evaluation, the scale can either be selfinformed, or otherinformed. Objective to compare the three aes sub scales subjectreported aess, informant reported aesi, and clinicianreported aescover time in individuals at risk for ad due to mci and advanced age cognitively normal. The apathy evaluation scale aes is a promising tool for measuring apathy in early ad. The interview is carried out with the subject andor an informant. Outcome measure frontal systems behavior scale frsbe sensitivity to change emerging evidence. Apathy evaluation scale self, informant, and clinician versions.
1682 1641 832 1000 503 1119 1229 1498 1464 1289 1192 1253 1320 902 227 744 22 1538 19 483 1018 964 82 1332 82 1477 20 355 1242 422 893 253 1270 687 1270 663 1264